Liu Wei Di Huang Wan: Ingredients, Uses and Safety

By TCMPath · Updated · Educational guide

Liu Wei Di Huang Wan is a six-ingredient classical formula associated with “Kidney Yin deficiency” in TCM. That traditional label is not a diagnosis of kidney disease, a hormone test result or a reason to take the formula simply because you feel tired or have night sweats.

What are the six ingredients?

The Hong Kong Baptist University formula database lists:

  • Shu Di Huang — prepared Rehmannia root.
  • Shan Zhu Yu — Cornus fruit.
  • Shan Yao — Chinese yam.
  • Ze Xie — Alisma rhizome.
  • Mu Dan Pi — tree peony root bark.
  • Fu Ling — Poria.

The classical explanation combines three nourishing ingredients with three ingredients described as draining or clearing. This is the logic of the traditional formula, not a modern measurement of what your organs need.

What does “Kidney Yin” mean here?

The capitalised word “Kidney” belongs to a traditional system of functions. It should not be equated with the anatomical kidneys. Dryness, warmth at night or fatigue can occur in many situations, so a symptom checklist cannot identify a formula or rule out illness.

This page explains a reference formula. It does not establish that a commercial product treats menopause, tinnitus, diabetes, kidney disease or age-related changes.

Is it the same as Zhi Bai or Qi Ju Di Huang Wan?

No. The HKBU reference describes related formulas with added ingredients: Zhi Bai Di Huang Wan adds Zhi Mu and Huang Bai; Qi Ju Di Huang Wan adds goji and chrysanthemum. Related names do not make the products interchangeable.

Check the full label rather than relying on the shared words “Di Huang.” Additions, substitutions and extract strengths can change what you are actually taking.

Side effects and medicine checks

It is not possible to give a reliable side-effect rate for every product sold under this name. Your exact product, health history and other medicines matter. NCCIH’s herb–drug interaction guidance explains why herbal products need to be considered in a medication review.

Ask the recommending professional what benefit is expected, what evidence supports it, what unwanted effects to watch for and when use will be reviewed. Seek advice if symptoms appear after starting any new product; do not simply label them a “healing reaction.”

How much should you take?

“Wan” refers to pills, but pill size and concentration are not universal. A historical dose cannot safely be copied onto an unrelated extract. TCMPath’s wellness service does not prescribe formulas or set medicinal doses.

If your real concern is night sweats or fatigue, start with appropriate assessment and a clear description of the symptom. Our related guides can help you prepare questions and organise daily routines.